Ebook (VitalSource) - £239.99

Publication date:

18 January 2017

Length of book:

570 pages

Publisher

Royal Society of Chemistry

ISBN-13: 9781782626602

Aging is a natural phenomenon that is peculiar to all living things. However, accumulating findings indicate that senescence could be postponed or prevented by certain approaches. Substantial evidence has emerged supporting the possibility of radical human health and lifespan extension, in particular through pharmacological modulation of aging. A number of natural dietary ingredients and synthetic drugs have been assumed to have geroprotective potential. In the development of anti-aging therapeutics, several cell, insect, and animal models may provide useful starting points prior to human studies.
This book provides an overview of current research aimed to search for life-extending medications and describes pharmacological aspects of anti-aging medicine. Readers are introduced to the fascinating historical background of geroprotection in the first chapter. In-depth information on models for investigating geroprotective drugs precedes a section covering anti-aging properties of pharmaceutical compounds, such as calorie restriction mimetics, autophagy inducers, senolytics and mitochondrial antioxidants. Finally, strategies to translate discoveries from aging research into drugs and healthcare policy perspectives on anti-ageing medicine are provided to give a complete picture of the field.
A timely and carefully edited collection of chapters by leading researchers in the field, this book will be a fascinating and useful resource for pharmacologists, gerontologists and any scientifically interested person wishing to know more about the current status of research into anti-aging remedies, challenges and opportunities.
This book would be of interest to a broad audience of scientists who investi-gate mechanisms underlying biological aging and age-related pathologies, medicinal chemists who implement knowledge of these mechanisms into the development of pharmacological geroprotectors for extending human lifespan and healthspan, clinicians who use these geroprotectors to treat various age-related diseases, and medical and university students who study in these fields of research and medical practice. The book would provide fundamental knowledge and thought-provoking new idea in all these fields of research and medical practice.